Hi there, thank you for joining me as I show you, step by step, how to use the BENLYSTA Autoinjector, also known as belimumab, for once-weekly, subcutaneous use.
Please remember that you should receive training from a healthcare professional before injecting for the first time.
Open on shot of the Benlysta PFP (unbranded) and other items needed laid on kitchen island.
Instructions for Use Video
Look at your package insert for full instructions on how to self-inject.
Benlysta (belimumab)
GSK
In the package insert leaflet of your BENLYSTA Autoinjector, you will find the Information for the User as well as the Instructions for Use. Read the full instructions on how to self-inject and refer to it throughout the injection process.
Be sure to follow the instructions on how to use the Autoinjector the right way. If you don’t, it may affect the proper function of the Autoinjector.
Long shot of female patient opening the instructions, flipping through them and putting them down on the counter.
Important Storage Information
Please take note of the following important storage information for the BENLYSTA Autoinjector:
Female patient walking up to her fridge and opening it to show the carton on the top shelf.
Important Storage Information
DO NOT freeze.
Do not freeze.
Camera pans down to the freezer and “no” symbol appears.
Important Storage Information
DO NOT use if left at room temperature for more than 12 hours.
Also, keep your Autoinjector away from heat and sunlight.
Do not use if left at room temperature for more than 12 hours. Also, keep your Autoinjector away from heat and sunlight.
Carton appears on counter and “no” symbol appears.
Important Warnings
The BENLYSTA Autoinjector should be used only once and then disposed of safely.
The BENLYSTA Autoinjector should be used only once and then discarded.
Female patient mimics use and tosses Autoinjector into the bin.
Important Warnings
DO NOT share your Autoinjector with another person.
DO NOT share your Autoinjector with another person.
Female patient attempts to share with the viewer.
Important Warnings
DO NOT shake.
DO NOT shake.
Female patient shakes Autoinjector and “no” symbol appears
Important Warnings
DO NOT use if dropped onto a hard surface.
Do not use if dropped onto a hard surface.
Female patient drops and pretends to use Autoinjector. “No: symbol appears.
Important Warnings
DO NOT remove the ring cap until right before the injection.
Do not remove the ring cap until right before the injection.
Female patient removed the ring cap and then puts it down. “No” symbol appears.
BENLYSTA Autoinjector Parts
Inspection Window
Grey Stopper
Ring Cap
Gold Needle Guard
Expiry Date
Now, it’s important to know all the Autoinjector parts so you know what to look for when following along.
The Autoinjector contains an inspection window and a grey stopper, which you will need to watch during the injection. Later, when it is time to remove the ring cap, you will see a gold needle guard, but the needle is not visible. The Autoinjector also has an expiry date; it’s important that you do not use the Autoinjector if the expiration date has passed.
Female patient holds up the Autoinjector and points to the different parts.
Supplies Needed for the Injection
The BENLYSTA Autoinjector
Alcohol swab (not included)
Gauze pad or cotton ball (not included)
Empty container with a tight-fitting lid (not included)
In addition to the BENLYSTA Autoinjector, you will need the following items; an alcohol swab, a gauze pad or cotton ball, and an empty container with a tight-fitting lid for Autoinjector disposal. These materials are not included in the pack, so make sure you have them on hand before you inject.
Female patient opening cupboards and drawers as she gathers her supplies.
Supplies Needed for the Injection
Now that we’ve covered off the basics, let’s grab a fresh Autoinjector from the fridge and set ourselves up in a comfortable space.
Female patient grabs a single tray from the fridge and walks over to the living room where there is a nice clean coffee table with all her items ready for use.
Supplies Needed for the Injection
Find a comfortable space to do the injection.
Make sure you have a clean and well-lit surface.
Place the Autoinjector, alcohol swab, gauze pad or cotton ball, and an empty container within reach.
Where you set up should also be well lit, with a clean surface that you can place the Autoinjector, alcohol swab, gauze pad or cotton ball, and an empty container that’s easy to reach.
Supplies Needed for the Injection
DO NOT perform the injection if you do not have all the supplies shown here.
If you don’t have these items, do not self-inject. But if you do, let’s get started.
Shot of supplies
Injection Preparation
Peel back the film of the tray and remove the Autoinjector.
Peel back the film of the tray and remove the Autoinjector carefully.
Female patient opens up the tray and checks out Autoinjector.
Injection Preparation
Check the expiration date on the Autoinjector.
DO NOT use if the expiration date has passed.
Label could look slightly different.
Now it’s time to prep and inspect your Autoinjector.
Check if the expiration date has passed. If it has, do not use it.
View of Autoinjector. “No” symbol appears.
Injection Preparation
Allow the Autoinjector to sit at room temperature for 30 minutes.
If you are doing the injection with me, it is time to let your Autoinjector sit at room temperature for 30 minutes. When your timer goes off, come back, and we will continue with the injection.
Clock counts down 30 minutes. Our patient goes through a series of scenes depicting what not to do.
Injection Preparation
DO NOT warm in a microwave oven, hot water, or direct sunlight.
This looks like a good time to mention some things that you shouldn’t do to warm up your Autoinjector.
Injection Preparation
DO NOT warm in a microwave oven, hot water, or direct sunlight.
DO NOT warm up the Autoinjector in any other way.
Do not put in the microwave or hot water or direct sunlight.
Be sure not to warm up the Autoinjector in any other way.
Female patient puts Autoinjector into microwave. “No” symbol appears.
Female patient puts Autoinjector in hot water. ‘No” symbol appears.
Female patient puts Autoinjector in the sun. “No” symbol appears.
Injection Preparation
DO NOT remove the ring cap during this step.
Do not remove the ring cap yet.
Female patient removing ring cap. “No” symbol appears.
Pause for 30 Minutes
Ok, pause the video, and I’ll see you in 30 minutes.
ON-SCREEN TEXT:
Injection Preparation
After 30 minutes, look in the inspection window to check that the solution is colourless to slightly yellow in colour.
After 30 minutes, look at the inspection window to check that the solution is colourless to slightly yellow in colour.
Female patient holds up the Autoinjector and brings it close to the camera
Injection Preparation
DO NOT use if the solution looks cloudy, discoloured, or has particles.
Do not use if the solution looks cloudy, discoloured, or has particles.
Female patient holding up Autoinjector. “No symbol” appears.
Injection Preparation
It is normal to see one or more air bubbles in the solution.
It is normal to see one or more air bubbles in the solution, so don’t worry if you see some.
Female patient holding up Autoinjector with air bubbles.
Injection Preparation
Choose an injection site.
There are only a couple places we recommend for the injection – in the abdomen or on the thighs.
Camera pulls back to reveal the injection sites highlight over female patient body
Injection Preparation
Avoid injecting into the same site each time and areas where the skin is tender, bruised, red, or hard.
Keep in mind that you want to avoid injecting into the same exact spot each time and try to avoid areas where the skin might be tender, bruised, red, or hard.
Camera pulls in to show the thigh. As female patient points to them, they are highlighted.
Injection Preparation
DO NOT inject within 2 inches of the belly button.
And do not inject within 2 inches of the belly button.
Female patient belly button appears with measurements. “No” symbol appears.
Injection Preparation
Wash your hands.
For this injection, I have chosen my thigh.
Once you’ve decided on an injection site, it’s time to wash your hands.
Female patient washes her hands thoroughly in the kitchen.
Injection Preparation
With clean hands, clean the injection site by wiping it with an alcohol swab.
Allow the skin to air dry.
When your hands are clean, wipe the injection site with an alcohol swab. Wait a little bit and allow the skin to air dry.
Female patient Is back in the living room washing her thigh with an alcohol swab.
Injection Preparation
DO NOT touch this area again before giving the injection.
Do not touch this area again before giving the injection.
Injection Preparation
Remove the ring cap by pulling or twisting it off.
The ring cap may be twisted off in either a clockwise or counter-clockwise direction.
Now it’s time to prepare for the actual injection.
You can remove the ring cap by pulling or twisting it off. The ring cap may be twisted off in either a clockwise or counter-clockwise direction.
Close up of the injection process appears. Female patient removes the ring cap.
Injection Preparation
DO NOT put the ring cap back onto the Autoinjector.
Once you’ve removed it, do not put the ring cap back onto the Autoinjector.
Female patient puts the ring cap back on Autoinjector. “No” symbol appears.
Injection Process
Hold the Autoinjector comfortably so that you can view the inspection window. This is important so that you can confirm a complete dose.
The positioning of the Autoinjector is another important thing to focus on.
Hold the Autoinjector comfortably so that you can view the inspection window. This is important so that you can confirm a complete dose.
Female patient grips the Autoinjector comfortably and shows how to firm the skin while positioning the Autoinjector over her thigh.
Injection Process
If needed, firm the injection site by pulling or stretching the skin.
If you need to, you can firm the injection site by pulling or stretching the skin like so.
View of Autoinjector over female patient leg.
Injection Process
Position the Autoinjector straight over the injection site. Make sure the gold needle guard is flat on the skin.
Position the Autoinjector straight over the injection site, and make sure the gold needle guard is flat on the skin. You want to create a 90-degree angle with the Autoinjector and your leg.
View of Autoinjector over female patient leg. 90 degrees angle icon appears.
Injection Process
Firmly press the Autoinjector all the way down onto the injection site and hold it in place.
It’s finally time to make the injection.
Firmly press the Autoinjector all the way down onto the injection site and hold it in place.
Close-up of the Autoinjector being injected.
Injection Process
This will insert the needle and start the injection.
This will insert the needle and start the injection.
Autoinjector being injected with 15 second timer appearing.
Injection Process
You may hear a first click at the start of the injection, and you will see the purple indicator start to move through the inspection window.
You may hear a first click at the start of the injection, and you will see the purple indicator start to move through the inspection window.
Autoinjector being injected with 15 second timer counting down.
Injection Process
You may hear a second click, but continue to hold the Autoinjector down until you see that the purple indicator has stopped moving.
The injection may take up to 15 seconds, so it is important to hold the Autoinjector down until you see the purple indicator has stopped moving.
Purple indicator begins to move
Injection Process
The injection may take up to 5 seconds to complete.
When the injection is complete, lift the Autoinjector from the injection site.
Female patient lifts Autoinjector off the leg.
After the Injection
Dispose of the used Autoinjector and ring cap in a container with a tight-fitting lid.
Now you can place the used Autoinjector and ring cap in the container with a tight-fitting lid.
Female patient puts the Autoinjector into a container with tight-fitting lid.
After the Injection
A small amount of blood is normal.
You can now inspect your injection site.
If you see a small amount of blood, this is completely normal. If needed, press a cotton ball or gauze pad on the injection site.
Female patient inspects the injection site.
After the Injection
DO NOT rub the injection site.
And remember, do not rub the injection site.
Female patient rubbing the injection site. “No” symbol appears.
After the Injection
Dispose of your Autoinjector correctly.
It is important you dispose of your Autoinjector correctly. Disposal facilities vary depending on where you live.
Female patient puts the Autoinjector in the regular garbage.
After the Injection
Ask your doctor or pharmacist for instructions on how to properly dispose of a used Autoinjector or filled container.
If you’re not sure how to properly dispose of a used Autoinjector or filled container, simply ask your doctor or pharmacist, and they will give you some safe disposal options.
Female patient walks towards a kitchen cupboard and with the container, opens it.
After the Injection
Always keep the filled container out of the reach of children.
Always keep the filled container out of the reach of children.
Female patient puts container in a high cupboard.
Benlysta (belimumab)
GSK
©2024 GSK group of companies or its licensor.
Trademarks are owned by or licensed to the GSK group of companies.
103835
06/24
PAAB
IMC
There you have it. Now you know all the steps to properly self-inject with your BENLYSTA Autoinjector.
If there was anything you didn’t understand, this video will always be here for your reference. If you have any additional questions, please ask your doctor or nurse.